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A unique system/disease-based approach to learning pulmonary pathophysiology as it relates to clinical medicine No other review puts disorders of lung structure and function in such clear clinical perspective as Pulmonary Pathophysiology. Bridging the gap between basic science and clinical medicine, Pulmonary Pathophysiology guides you from symptom identification to underlying disease mechanisms and through principles of management. Features: 28 case studies help you understand the correlation between science and clinical medicine Additional algorithms aid differential diagnosis and management Key Concepts help you quickly review chapter highlights New tables and charts encapsulate important information Learning Objectives and study questions reinforce your understanding of even the most difficult topics Artwork includes nearly 100 photographs and line drawings Visit www.LangeTextbooks.com to access valuable resources and study aids!
Updated and revised, this new edition of Caplan's Stroke continues to provide a concise and pragmatic approach to the evaluation, diagnosis, and management of adult and pediatric stroke patients. Dr. Caplan-a highly esteemed stroke authority- shares with you his vast experience and wisdom as a stroke clinician, including his time-tested strategies and unique clinical pearls that you can implement into your own practice. Expanded coverage of imaging and laboratory diagnosis and treatment as well as extensive revisions throughout, brings you the latest advances on prevention, complications, and rehabilitation. The use of case studies illustrates the types of clinical scenarios you may experience in practice. And, its conversational, easy-to-read format make Caplan's Stroke an ideal resource for general neurologists, non-neurologists, and stroke specialists alike. Discusses all cerebrovascular diseases to help you differentiate among all types of stroke so you can treat each patient appropriately. Takes a distinctly personal and individual approach to general principles, pathophysiology, diagnosis, treatment, and rehabilitation, offering practical, clinical guidance on stroke and stroke related issues. Provides detailed discussions on stroke syndromes in children and adults, including large artery occlusive disease of the anterior circulation, brain embolism, spinal cord stroke, and many, many more, to help you better manage every condition you see. Uses case studies to highlight and emphasize clinical points. Includes expanded coverage of imaging and laboratory diagnosis and treatment to help you make better informed evaluation and management decisions. Presents meticulous revisions and updates throughout, particularly to the chapters on stroke prevention and rehabilitation to keep you current on today's best practices. Features a new two-color design with updated artwork and more images that elucidates key points and enhances visual guidance.
This reference thoroughly equips you to successfully diagnose and manage even the most complex incidences of diastolic heart failure and their comorbidities. It examines the basic mechanisms of this condition through discussions of both cellular and anatomic causes; guides you through non-invasive techniques for diagnosis, including echocardiography, cardiac CT, and MRI; and provides expert advice on pharmacologic management. Covers the basic mechanisms of diastolic heart problems from both cellular and anatomic perspectives. Chapters covering modalities helpful in assessment of diastolic function such as: echocardiography, cardiac MRI, radionuclide ventriculography, and invasive hemodynamic measurements. Features in-depth assessments of all diagnostic methods for diastolic heart failure, including rationales for their use. Examines contributing conditions that play a role in diastolic heart failure and offers guidance on their management. Offers pharmacologic strategies for multiple problem management.
This completely new textbook takes an integrative, problem-based approach to pathophysiology, creating an effective bridge from basic science to clinical practice. Preeminent pathology practitioner, author, and instructor Ivan Damjanov, MD, PhD skillfully provides you with the rich understanding of disease mechanisms you need to succeed on the USMLE and beyond. Clinical vignettes in each chapter, presented in a problem-based format, demonstrate the practical relevance of pathophysiology principles, and hundreds of full-color diagrams clarify even the most difficult concepts. The result is a comprehensive yet succinct source that is ideal for today's medical students. Discussions of each organ system's disorders include key clinical function tests and lab tests - valuable aspects of laboratory medicine that are highly relevant to clinical practice, but are not covered in other pathophysiology texts. A consistent, logical format for each chapter makes the material easy to master. Abundant full-color conceptual diagrams, algorithms, and charts present complex information in an easy-to-absorb manner. Glossaries of key terms, review questions, and other learning tools facilitate study. Clinical case studies help you succeed in problem-based learning courses and on the USMLE.
Pheochromocytomas are rare, mostly benign tumors of the adrenal medulla whose symptoms are caused by a tumor-induced secretion of catecholamines. This book provides an overview of current knowledge on the clinical situation, diagnosis and therapy of the disease as well as an extensive discussion of novel aspects in the molecular basis of this disease such as the recognition of new tools in molecular biology. The endocrine diagnosis is based on precise knowledge of tumor metabolism of catecholamines and their metabolites and today comprises laboratory methods with a high sensitivity and specificity. As approximately one quarter of these tumors arise in the context of a familial disease, such as multiple endocrine neoplasia type 2, von Hippel-Lindau syndrome, neurofibromatosis type 1 or familial paragangliomas, the genetic diagnosis is becoming increasingly relevant. Equally indispensable are imaging methods such as 123I-MIBG scintigraphy or octreotide scintigraphy, which can be employed as a complementary approach in e.g. malignant tumors. The surgical therapy is clearly based on the nature of the disease; in sporadic unilateral as well as familial bilateral pheochromocytoma a lateral endoscopic approach is chosen. The treatment of malignant pheochromocytoma is mainly based on the use of nuclear medical techniques and selected chemotherapeutic approaches. This book is essential reading for clinicians and scientists in the fields of endocrinology as well as oncology, surgery and nuclear medicine.
La segunda edición de Fisiopatología. Un enfoque clínico ofrece una perspectiva clínica únicaque facilita el aprendizaje presentando la fisiopatología como la ven los profesionales sanitarios. Mientras que un abordaje tradicional organizado por sistemas aísla de forma poco práctica las enfermedades y las relaciona con único sistema corporal, este manual describe cómo las distintas patologías afectan a múltiples sistemas. Además, en lugar de ocuparse de un número limitado de enfermedades, fomentando la repetición mecánica de los factores clave de las mismas, el abordaje clínico describe en detalle los mecanismos de cada enfermedad. Al dominar los principales conceptos de la función humana alterada, los estudiantes obtienen una comprensión más profunda de múltiples afecciones, en lugar de memorizar datos sobre enfermedades concretas. El lector adquiere conocimientos poniendo en práctica los conceptos, de este forma aprende a pensar sobre la fisiolopatología del mismo modo en que tendrá que pensar en un entorno clínico, trabajando a partir de los síntomas hasta la causa, en lugar de al contrario. Cada capítulo describe modelos clínicos, mejorando así la aplicación de este material a la práctica diaria.
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