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Easy to read and comprehensive, Survival Analysis Using SAS: A Practical Guide, Second Edition, by Paul D. Allison, is an accessible, data-based introduction to methods of survival analysis. Researchers who want to analyze survival data with SAS will find just what they need with this fully updated new edition that incorporates the many enhancements in SAS procedures for survival analysis in SAS 9. Although the book assumes only a minimal knowledge of SAS, more experienced users will learn new techniques of data input and manipulation. Numerous examples of SAS code and output make this an eminently practical book, ensuring that even the uninitiated become sophisticated users of survival analysis. The main topics presented include censoring, survival curves, Kaplan-Meier estimation, accelerated failure time models, Cox regression models, and discrete-time analysis. Also included are topics not usually covered in survival analysis books, such as time-dependent covariates, competing risks, and repeated events. Survival Analysis Using SAS: A Practical Guide, Second Edition, has been thoroughly updated for SAS 9, and all figures are presented using ODS Graphics. This new edition also documents major enhancements to the STRATA statement in the LIFETEST procedure; includes a section on the PROBPLOT command, which offers graphical methods to evaluate the fit of each parametric regression model; introduces the new BAYES statement for both parametric and Cox models, which allows the user to do a Bayesian analysis using MCMC methods; demonstrates the use of the counting process syntax as an alternative method for handling time-dependent covariates; contains a section on cumulative incidence functions; and describes the use of the new GLIMMIX procedure to estimate random-effects models for discrete-time data. This book is part of the SAS Press program.
In this follow-up to "Extending SAS Survival Analysis Techniques for Medical Research," the theory and methods of survival analysis and SAS procedures used to implement the methods are fully described. The new features, along with several useful macros and numerous examples, make this edition a suitable textbook for a course in survival analysis for biostatistics majors and majors in related fields.
Analysis of Clinical Trials Using SAS®: A Practical Guide, Second Edition bridges the gap between modern statistical methodology and real-world clinical trial applications. Tutorial material and step-by-step instructions illustrated with examples from actual trials serve to define relevant statistical approaches, describe their clinical trial applications, and implement the approaches rapidly and efficiently using the power of SAS. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials. Commonly used methods are covered, including dose-escalation and dose-finding methods that are applied in Phase I and Phase II clinical trials, as well as important trial designs and analysis strategies that are employed in Phase II and Phase III clinical trials, such as multiplicity adjustment, data monitoring, and methods for handling incomplete data. This book also features recommendations from clinical trial experts and a discussion of relevant regulatory guidelines. This new edition includes more examples and case studies, new approaches for addressing statistical problems, and the following new technological updates: SAS procedures used in group sequential trials (PROC SEQDESIGN and PROC SEQTEST) SAS procedures used in repeated measures analysis (PROC GLIMMIX and PROC GEE) macros for implementing a broad range of randomization-based methods in clinical trials, performing complex multiplicity adjustments, and investigating the design and analysis of early phase trials (Phase I dose-escalation trials and Phase II dose-finding trials) Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience and the ready-to-use SAS macros compiled in this book.
Statisticians and researchers will find Categorical Data Analysis Using SAS, Third Edition, by Maura Stokes, Charles Davis, and Gary Koch, to be a useful discussion of categorical data analysis techniques as well as an invaluable aid in applying these methods with SAS. Practical examples from a broad range of applications illustrate the use of the FREQ, LOGISTIC, GENMOD, NPAR1WAY, and CATMOD procedures in a variety of analyses. Topics discussed include assessing association in contingency tables and sets of tables, logistic regression and conditional logistic regression, weighted least squares modeling, repeated measurements analyses, loglinear models, generalized estimating equations, and bioassay analysis. The third edition updates the use of SAS/STAT software to SAS/STAT 12.1 and incorporates ODS Graphics. Many additional SAS statements and options are employed, and graphs such as effect plots, odds ratio plots, regression diagnostic plots, and agreement plots are discussed. The material has also been revised and reorganized to reflect the evolution of categorical data analysis strategies. Additional techniques include such topics as exact Poisson regression, partial proportional odds models, Newcombe confidence intervals, incidence density ratios, and so on. This book is part of the SAS Press program.
THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.
This book guides researchers in performing and presenting high-quality analyses of all kinds of non-randomized studies, including analyses of observational studies, claims database analyses, assessment of registry data, survey data, pharmaco-economic data, and many more applications. The text is sufficiently detailed to provide not only general guidance, but to help the researcher through all of the standard issues that arise in such analyses. Just enough theory is included to allow the reader to understand the pros and cons of alternative approaches and when to use each method. The numerous contributors to this book illustrate, via real-world numerical examples and SAS code, appropriate implementations of alternative methods. The end result is that researchers will learn how to present high-quality and transparent analyses that will lead to fair and objective decisions from observational data. This book is part of the SAS Press program.
Critically acclaimed and resoundingly popular in its first edition, Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advances--particularly in software--made in the field over the last 10 years. Now, more than ever, it provides an outstanding text for upper-level and graduate courses in survival analysis, biostatistics, and time-to-event analysis.The treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data, including the Cox regression model, the Weibull proportional hazards model, and others. This edition features a more detailed treatment of topics such as parametric models, accelerated failure time models, and analysis of interval-censored data. The author also focuses the software section on the use of SAS, summarising the methods used by the software to generate its output and examining that output in detail. Profusely illustrated with examples and written in the author's trademark, easy-to-follow style, Modelling Survival Data in Medical Research, Second Edition is a thorough, practical guide to survival analysis that reflects current statistical practices.

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