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Contact lenses are not without risks. They rest directly on the tear film, which lubricates the cornea and conjunctiva. They have the potential to disrupt the tear film and the normal physiology of the ocular surface. Hypoxia associated with contact lens wear is thought to facilitate the development of complications such as vascularization, edema, corneal ulcers, contact lens-superior limbic keratoconjunctivits (CL-SLK), corneal striae, limbal hyperemia, and epithelial microcysts. Contamination is another major concern. Acanthamoeba keratitis is a rare but dangerous corneal infection with the protozoan commonly found in soil, dust, and freshwater. Different strains of Pseudomonas aeruginosa are common culprits of inflammation and infection as seen with contact lens induced acute red eye (CLARE) reactions and ulcerative keratitis. Contact lens-induced peripheral ulcers (CLPU) are non-infectious peripheral corneal ulcers with infiltrates that must be differentiated from ulcerative keratitis. Giant papillary conjunctivitis (GPC) is a complication with a multifactorial etiology and a strong immunological component. Tear film debris can be associated with mucin balls and contact lens deposits. Proper fitting and follow-up of contact lenses is important to reduce the incidence of many contact lens complications, such as superior epitheal arcuate lesion (SEAL), corneal compression ring (CCR), and CL-SLK. Superficial punctate keratitis (SPK) is very common in contact lens wearers. It may be secondary to many things, including dry eye, solution hypersensitivity, poor fitting lenses, or inadequate oxygen supply to the cornea. The purpose of this literature review is to identify hydrogel contact lens complications, their causes, and management in order to better educate patients about a particular hydrogel contact lens complication. A patient educational CD was developed to allow the patient to take home printed educational material about their contact lens complication.