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This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.
A Handbook of Gene and Cell Therapy
Language: en
Pages: 188
Authors: Clévio Nóbrega, Liliana Mendonça, Carlos A. Matos
Categories: Medical
Type: BOOK - Published: 2020-06-27 - Publisher: Springer Nature

This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of
Gene and Cell Therapy
Language: en
Pages: 1120
Authors: Nancy Smyth Templeton
Categories: Science
Type: BOOK - Published: 2008-10-06 - Publisher: CRC Press

Since the publication of the second edition of this book in 2004, gene therapy and cell therapy clinical trials have yielded some remarkable successes and some disappointing failures. Now in its third edition, Gene and Cell Therapy: Therapeutic Mechanisms and Strategies assembles many of the new technical advances in gene
Gene Therapy and Cell Therapy Through the Liver
Language: en
Pages: 185
Authors: Shuji Terai, Takeshi Suda
Categories: Medical
Type: BOOK - Published: 2015-10-16 - Publisher: Springer

This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the current aspects and future prospects from basic research to clinical therapies. Edited by pioneering researchers, this volume presents extensive information to principal investigators, researchers, postdocs and clinicians
Gene and Cell Therapy
Language: en
Pages: 896
Authors: Nancy Smyth Templeton
Categories: Science
Type: BOOK - Published: 2003-12-17 - Publisher: CRC Press

This reference is completely revised and expanded to reflect the most critical studies, controversies, and technologies impacting the medical field, including probing research on lentivirus, gutless adenovirus, bacterial and baculovirus vectors, retargeted viral vectors, in vivo electroporation, in vitro and in vivo gene detection systems, and all inducible gene expression
Therapeutic Applications of Adenoviruses
Language: en
Pages: 256
Authors: Philip Ng, Nicola Brunetti-Pierri
Categories: Medical
Type: BOOK - Published: 2016-12-12 - Publisher: CRC Press

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy