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A FEVER IN THE HEART covers the real life drama of a love triangle that ended in tragedy, shocking the tight knit community of Yakima, Washington. What began as an innocent flirtation erupted into an affair that destroyed many lives. At its center were three people so charismatic, attractive and intelligent, that they should have had decades of happiness ahead of them. But three is a crowd, and the odd man out wanted back in--at any cost. But was he capable of murder? Supporters said no, and pointed out he had an airtight alibi. Yet someone hatched a fatal scheme so unbelievable it could be a plot from a Hitchcock film. Ann Rule first covered this case for COSMOPOLITAN magazine in 1976. But Olive Blankenbaker, mother of one of the victims, begged Rule to dig deeper and write an entire book. Rule promised Olive that she would. It took twenty years, but she kept her promise to Olive. Rule's thorough research of one of the most fascinating cases she has ever found brings A FEVER IN THE HEART to life and keeps true crime fans riveted.
Get a quick, expert overview of the many key facets of heart failure research with this concise, practical resource by Dr. Longjian Liu. This easy-to-read reference focuses on the incidence, distribution, and possible control of this significant clinical and public health problem which is often associated with higher mortality and morbidity, as well as increased healthcare expenditures. This practical resource brings you up to date with what’s new in the field and how it can benefit your patients. Features a wealth of information on epidemiology and research methods related to heart failure. Discusses pathophysiology and risk profile of heart failure, research and design, biostatistical basis of inference in heart failure study, advanced biostatistics and epidemiology applied in heart failure study, and precision medicine and areas of future research. Consolidates today’s available information and guidance in this timely area into one convenient resource.
"Covering all aspects of CHDs, the chapters include important discussions on development, epidemiology, genetics, diagnosis, management, and prevention of these birth defects, as well as coverage of public health issues such as environmental risk factors and healthcare costs related to CHDs. This book will be of interest to geneticists, epidemiologists, cardiologists, pediatricians, graduate students, researchers, and others interested in the treatment of individuals' with CHDs." --Book Jacket.
Whenever the heart is challenged with an increased work load for a prolonged period, it responds by increasing its muscle mass--a phenomenon known as cardiac hypertrophy. Although cardiac hypertrophy is commonly seen under physiological conditions such as development and exercise, a wide variety of pathological situa tions such as hypertension (pressure overload), valvular defects (volume overload), myocardial infarction (muscle loss), and cardiomyopathy (muscle disease) are also known to result in cardiac hypertrophy. Various hormones such as catecholamines, thyroid hormones, angiotensin II, endothelin, and growth factors have also been shown to induce cardiac hypertrophy. Although the exact mechanisms underlying or pathological forrns of cardiac hypertrophy are poorly under the physiological stood, an increase in the intraventricular pressure is believed to represent the major stimulus for the development of cardiac hypertrophy. In this regard, stretching of the cardiac muscle has been shown to induce the hypertrophic response, but the role of metabolic influences in this process cannot be ruled out. Furthermore, different hormones and other interventions in the absence of stretch have been observed to stimulate protein synthesis in both isolated cardiomyocyte and vascular myocyte preparations. Nonetheless, it is becoming dear that receptor as well as phospholipid linked signal transduction pathways are activated in some specific manner depend ing upon the initial hypertrophic stimulus, and these then result in an increase in the size and mass of cardiomyocytes.
Describes and examines the attempts of Gush Emunim, a religious nationalistic social movement, to construct Israeli identity, collective memory, and sense of place.
Stephen King, whose first novel, Carrie, was published in 1974, the year before the last U.S. troops withdrew from Vietnam, is the first hugely popular writer of the TV generation. Images from that war -- and the protests against it -- had flooded America's living rooms for a decade. Hearts in Atlantis, King's newest fiction, is composed of five interconnected, sequential narratives, set in the years from 1960 to 1999. Each story is deeply rooted in the sixties, and each is haunted by the Vietnam War. In Part One, "Low Men in Yellow Coats," eleven-year-old Bobby Garfield discovers a world of predatory malice in his own neighborhood. He also discovers that adults are sometimes not rescuers but at the heart of the terror. In the title story, a bunch of college kids get hooked on a card game, discover the possibility of protest...and confront their own collective heart of darkness, where laughter may be no more than the thinly disguised cry of the beast. In "Blind Willie" and "Why We're in Vietnam," two men who grew up with Bobby in suburban Connecticut try to fill the emptiness of the post-Vietnam era in an America which sometimes seems as hollow -- and as haunted -- as their own lives. And in "Heavenly Shades of Night Are Falling," this remarkable book's denouement, Bobby returns to his hometown where one final secret, the hope of redemption, and his heart's desire may await him. Full of danger, full of suspense, most of all full of heart, Stephen King's new book will take some readers to a place they have never been...and others to a place they have never been able to completely leave.

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