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Cardiovascular disease is the major cause of morbidity and mortality worldwide. While the past 40 years have brought major progress in cardiac valve repair and replacement, there remain large patient populations that do not receive such therapies. This, in turn, implies a great need for future basic, applied, and clinical research and, ultimately, therapeutic developments. Heart Valves is a state-of-the-art handbook dedicated to: 1) cardiac valve anatomy, 2) models for testing and research methods; 3) clinical trials; and 4) clinical needs and applications.
This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.
This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
The landscape of cardiac surgery is changing, as is the field of interventional cardiology. The idea of accessing and replacing a failing valve through the patients vasculature has become the most rapidly expanding therapy of choice in cardiovascular disease. Transcatheter Valve Therapies chronicles the astonishing advances that have taken place in the field and prepares readers for the challenging future of cardiac valve therapies. Designed to meet the growing needs of cardiologists, cardiac surgeons, anesthetists, and general practitioners, the book covers all aspects from logistic needs to clinical outcomes. It provides a comprehensive overview of transcatheter valve therapies and the necessary understanding for a successful clinical introduction at individual institutions. Topics include: Epidemiologic considerations Aspects of balloon aortic valvuloplasty as a stand-alone procedure or as part of the transcatheter valve replacement The history of how transcatheter valve therapies were implemented into surgical practice New imaging modalities The particularities of transcatheter access Aortic root anatomy Emerging technologies and future design improvements Development steps of aortic devices and potential solutions for transcatheter tricuspid, mitral, and pulmonary valve replacement The rigorous testing requirements for endovascular medical devices Clinical results of aortic transcatheter valve therapies in easy accessible text and table formats The future of transcatheter valve therapies All topics are discussed based on the author’s own clinical and experimental experience in the field. This volume is essential for anyone involved in transcatheter valve implantation, clinicians wishing to become more involved in improving transcatheter valve therapies, and researchers engaged in building and creating new medical technologies to shape the cardiovascular landscape of the future.
Weare entering an especially prolific era in reporting and publishing clinical experiences with cardiac valve replacement. A voluminous litera ture on this subject is already in existence, emanating from clinicians, surgeons, bioengineers, and other scientists. Additionally, information presented at heart valve symposia in the form of bound collections reaches the shelves of the medical book stores every year. This activity reflects the dynamic state of cardiac valve technology, highlighted by the introduction each year of new valve designs that often utilize new materials. As a result, the authors recognized the need to update their book The Pacemaker and Valve Identification Guide, separating the contents into two volumes dealing with pacemakers* and cardiac valve technology. For this Guide to Prosthetic Cardiac Valves, we have gathered a group of recognized authorities in the field, all of whom have contributed in depth analysis in their areas of expertise. New material dealing with the preoperative and postoperative care ofthe heart valve patient, pathol ogy of cardiac valves, bioengineering problems of cardiac valve technol ogy, and separate chapters on valve implantation in children and ultra sonography have been added. Chapter 3, "The Radiology of Prosthetic Heart Valves," we feel will be particularly helpful to the physician in identifying a prosthetic valve and revealing the most likely complica tions. Chapter 10 is an atlas with descriptions to supply the reader with the essential features of the various prostheses when he or she is faced with a new patient bearing an implanted cardiac valve.
Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ("Cardiac Reconstructions with Allograft Valves") in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table. All surgeons performing pediatric and/or adult valve replacements and reconstructive cardiac surgeries will benefit from the described methods. Cardiothoracic residents and cardiologists will also find the text useful. It will provide the surgeon with an enhanced understanding of the biological and material properties of allografts and increased familiarity with the range of surgical techniques applicable for the use of these valves, particularly in the successful management of challenging cardiac reconstructions.>
Internationally renowned cardiologists Drs. Catherine M. Otto and Robert O. Bonow help you to apply all of the latest scientific knowledge and clinical strategies with Valvular Heart Disease, a companion to Braunwald’s Heart Disease. This indispensable resource for your everyday practice provides all of the knowledge you need to give your patients the most accurate diagnoses, the best possible heart disease treatment options, and the expert care they deserve. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply today's best medical and surgical approaches with comprehensive, expert guidance on today's full range of clinical heart disease treatments. Provide appropriate care to pediatric and pregnant patients with focused chapters on the unique needs of these special populations. Update your knowledge of these increasingly common heart diseases with brand-new chapters covering 3-dimensional anatomy of the aortic and mitral valves; clinical and genetic risk factors for calcific valve disease; risk assessment for aortic and mitral valve surgery; image-guided transcatheter valve procedures; optimal timing of valve interventions; state-of-the-art valve surgery; and much more. Apply the most current standards of practice with summaries of the ACC/AHA and new ESC valvular heart disease guidelines in each chapter. Vividly visualize heart valve anatomy and dysfunction, as well as important techniques and procedures, thanks to a multitude of detailed illustrations, full-color images, and online video content. Search the full text and access all the images online at Expert Consult.

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