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There are numerous examples in the history of science when the parallel develop ments of two or more disciplines, methodologies, technologies or theoretical in sights have converged to produce significant scientific advances. The decades following the 1950s have produced several such significant advances, as a result of a convergence of developments in molecular biology and in solid state-based electronics instrumentation. Since one of these areas of significant advancement, analytical ultracentrifu gation, has been undergoing a renaissance, we thought it would be a useful activity to call upon a group of researchers who have been developing either the experi mental or theoretical aspects of the methodology and gather in one place a group of articles summarizing the current status of the field. The success of recombinant DNA methodologies at producing biologically active macromolecules of commer cial interest has evoked interests in mechanisms of function. Pursuit of the related questions has emphasized the importance of studies of macromolecular binding and interaction. Several contributions to this volume remind us that analytical ultra centrifugation is rigorously based on solid thermodynamic theory and, as such, is fully capable of providing comprehensive quantitative descriptions of molecular interactions in solution. Furthermore, a number of the chapters provide examples, along with innovative methods for carrying out these characterizations. The past decade has seen several developments that reflect the rebirth of interest in analytical ultracentrifugation.
Modern Analytical Ultracentrifugation
Language: en
Pages: 354
Authors: Todd M. Schuster, Thomas M. Laue
Categories: Science
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

There are numerous examples in the history of science when the parallel develop ments of two or more disciplines, methodologies, technologies or theoretical in sights have converged to produce significant scientific advances. The decades following the 1950s have produced several such significant advances, as a result of a convergence of
Modern Analytical Ultracentrifugation
Language: en
Pages: 372
Authors: Todd M Schuster, Thomas M Laue
Categories: Science
Type: BOOK - Published: 1994-08-01 - Publisher:

Books about Modern Analytical Ultracentrifugation
Analytical Ultracentrifugation V
Language: en
Pages: 223
Authors: H. Cölfen
Categories: Technology & Engineering
Type: BOOK - Published: 2013-10-03 - Publisher: Springer

The basis for this volume is the 11th Symposium on Analytical Ultracentrifugation held in March 25-26, 1999 at the University of Potsdam, Germany. This book presents a comprehensive collection of 33 contributions from leading scientists in this field including: Technical and methodological innovations.- Innovations in data analysis.- Hydrodynamics/Modelling.- Synthetic polymers,
Ultracentrifugation
Language: en
Pages: 120
Authors: M. D. Lechner
Categories: Centrifugation
Type: BOOK - Published: 1994 - Publisher: Springer Verlag

Ultracentrifugation contains the proceedings of the VIII. same-named symposium held in 1993, at Osnabrück, FRG. The volume presents the current concepts in analytical ultracentrifugation (AUC) including: . biochemical and biophysical applications . characterization of polyelectrolytes, synthetic polymers, gels and lattices . modern, fully computerized analytical ultracentrifuge Optima XL-A . future
Sedimentation Velocity Analytical Ultracentrifugation
Language: en
Pages: 271
Authors: Peter Schuck, Huaying Zhao
Categories: Science
Type: BOOK - Published: 2017-09-22 - Publisher: CRC Press

Analytical ultracentrifugation is one of the most powerful solution techniques for the study of macromolecular interactions, to define the number and stoichiometry of complexes formed, and to measure affinities ranging from very strong to very weak and repulsive. Building on the data analysis tools described in the volume Sedimentation Velocity